Memory usage statistics for total designs The log(pre-filter) complexity was fit against memory and disk usage for MC_GA with number_MC_cycles 10000: predicted memory usage = 0.30536*(log(number_of_combinations))^1.339 predicted disk usage = 0.00073*(log(number_of_combinations))^1.45725 While these predictions are fairly accurate for designs, they significantly over-estimate the memory requirements for single-sequence rotamer optimization. In addition, the memory usage will also depend on the jobtype, number of cycles, etc. rotamer combinations name log(pre-filter) log(post-filter) memory (MB) disk (K) RNaseH 352.062062 301.571706 766 3439524 zif268 67.307383 59.418546 92.94 329444 villin 85.428085 72.929368 104 426788 srcSH3 132.027056 114.230075 198 952732 cspA 147.557805 128.530679 241 1089360 ci2 147.560046 129.609522 240 1031156 434cro 150.145516 127.773576 223 1130668 top7 225.221636 197.896053 482 2052192 gb1 134.612525 118.970587 230 970732 engrailed 129.437103 113.985092 211 905792 lambda_rep 204.505378 175.412394 354 1659488 fn10 201.921029 172.927599 336 1597528 fkbp 225.221636 195.501846 443 1903348 LB1 152.730985 134.410980 317 1135680 barnase 245.931169 213.287156 461 2148204 s6 230.399299 202.060858 470 2005636